Diagnostic Ultrasound

RBC aggregation analysis for circulatory disease diagnosis

Overview

RBC aggregation is an important rheological factor for predicting and diagnosing circulatory diseases. Many experimental and computational studies have been conducted. However, most in vivo and in-vitro studies were performed under steady Poiseuille flow. In our lab, we investigate the relationship between shear rate and RBC aggregation considering the spatial distribution under pulsatile flow.

Numerical simulation of RBC aggregation under pulsatile flow conditions.
Analysis of spatial distribution, ultrasound imaging, and 3D visualization techniques.

Research Fields

  • Numerical simulation for kinetics of RBC under Womersley flow in the elastic tube
  • Spatial distribution analysis of RBC aggregation in flow field (velocity, shear rate, acceleration field)
  • Observation of echo variation and carotid wall in rats on the ultrasound image
  • Implementation of three-dimensional ultrasound images for observation of variation of echo and vessel wall contraction and expansion in rat carotid artery